Pest Management Reporter
Industry Intelligence for Pest Management Professionals & Homeowners
Personal Protection  —  Mosquito & Tick Repellents
DEET • Picaridin • IR3535 • Oil of Lemon Eucalyptus • Repellent Duration • Missouri

Mosquito Repellent Guide: DEET vs. Picaridin vs. IR3535 — What the Evidence Shows

The EPA-registered insect repellent category has expanded significantly over the past decade, and the consumer choice between DEET, picaridin, IR3535, and plant-based options is no longer a simple default to whichever product is familiar. For Missouri's combination of mosquito and tick pressure from April through October, the choice of active ingredient and concentration matters for both protection duration and tick efficacy.

Pest Management Reporter Staff  •  Personal Protection Series

EPA-Registered Repellents Compared

Active IngredientMosquito DurationTick EfficacyNotes
DEET 20–30%4–8 hoursGoodLong-established efficacy record. Damages some plastics and synthetic fabrics. Safe for use per label on adults and children over 2 months. 30% is the recommended concentration for extended outdoor use in Missouri.
Picaridin 20%8–12 hoursGoodNo plastic/fabric damage. No odor. Increasingly the preferred alternative to DEET for outdoor workers and extended use. 20% concentration recommended for Missouri tick season.
IR3535 20%4–8 hoursModerateLower tick efficacy than DEET or picaridin at equivalent concentrations. Good option for mosquito protection where tick exposure is lower.
Oil of Lemon Eucalyptus (OLE)4–6 hoursGood at higher concentrationsPlant-derived but not the same as lemon eucalyptus essential oil. CDC-recommended. Not for use on children under 3. Requires more frequent reapplication.
Essential oil products (citronella, etc.)20–60 minutesPoorNot EPA-registered as repellents. Short duration, no tick efficacy. Not recommended for Missouri's tick season.

Application Notes for Missouri Conditions

Missouri's combination of mosquito and tick pressure during the same April–October window means repellent choice should prioritize products with documented tick efficacy — DEET 30% or picaridin 20% are the practical choices. Apply repellent to all exposed skin including ankles and sock line where ticks commonly attach. For clothing, permethrin-treated garments (which are insecticidal rather than repellent) provide the most effective tick protection and can be combined with any skin-applied repellent. Reapply per product label — sweat, water exposure, and time reduce efficacy. D&D Pest Control provides mosquito yard treatment and tick barrier programs for Franklin County and rural Missouri — visit ddpestcontrolmo.com.

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